Abstract Library
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ENETS Abstract Search
#2841 Novelties in Primary and Metastatic GEP-NENs Clinical Outcome Investigation
Introduction: Gastro-entero-pancreatic neuroendocrine neoplasms (GEP-NENs) WHO classification, using strict cut-offs, should reflect their biological features. In real world, strict cut-offs not adequately segregate prognostic groups, in particular on metastasis (M).
Conference: 17th Annual ENETSConcerence (2020)
Presenting Author: Milione M
Authors: Kankava K, Maisonneuve P, Mangogna A, Centonze G, Cattaneo L,
Keywords: Gastro-entero-pancreatic neuroendocrine neoplasms, primary tumor, metastasis, Ki-67, mitoses, tumor deposits, clinical outcomes,
Introduction: Treatment of advanced neuroendocrine tumors aims to relieve symptoms and suppress tumor growth. Primary findings from the TELEACE study suggested telotristat ethyl (TE) may reduce tumor size and impact tumor growth.
Conference: 17th Annual ENETSConcerence (2020)
Presenting Author: Metz D
Authors: Metz D, Liu E, Joish V, Huynh L, Cheng M,
Keywords: neuroendocrine tumor, carcinoid syndrome, telotristat ethyl, serotonin, tumor growth, progression-free survival,
Introduction: Several inflammatory response materials could be used for prediction of prognosis in cancer patients. The neutrophil lymphocyte ratio (NLR), platelet lymphocyte ratio (PLR), thrombocytosis (the platelets number >400*103/mm3) have been introduced for prognostic scoring system in various cancers.
Conference: 15th Annual ENETSConcerence (2018)
Presenting Author: croitoru A
Authors: Grigorescu R, Croitoru A, Stanel I, Gheorghe C, Grama I,
Keywords: prognostic factors, survival,
Introduction: MCC is a rare and aggressive skin cancer with a neuroendocrine phenotype.Association between MCC and Polyomavirus is known.PD-1 and PD-L1 have recently become key players in the therapeutic landscape.
Conference: 15th Annual ENETSConcerence (2018)
Presenting Author: Birocco N
Authors: Mecca C, Maletta F, Caliendo V, Birocco N, Metovic J,
Keywords: merkel cell carcinoma, microenvironment, polyomavirus,
#2108 Molecular Characterization of Primary and Metastatic Pancreatic Neuroendocrine Tumors
Introduction: Pancreatic neuroendocrine tumours (PNETs) are a heterogeneous group of rare pancreatic neoplasms often diagnosed with distant metastases, which are associated with significantly poorer prognosis. Recurrent somatic mutations, chromosomal aberrations and gene expression signatures in PNETs have been described, but the clinical significance of these molecular changes is still poorly understood, and the clinical outcomes of PNET patients remain highly variable.
Conference: 15th Annual ENETSConcerence (2018)
Presenting Author:
Authors: Yang K, Wong H, Shen Y, Colborne S, Kalloger S,
Keywords: pancreatic neuroendocrine tumor, metastasis, primary tumor, proteomics, transcriptomics,